Tetrazole formation by cycloaddition


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The azide and the nitrile undergo 1,3-dipolar cycloaddition to give the tetrazole anion. The anion is then protonated on workup to give the final tetrazole product.

S. Das, S. Santra, P. Mondal, A. Majee and A. Hajra, Synthesis (Stuttg)., 2016, 48, 1269–1285.


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