Click the structures and reaction arrows in sequence to view the 3D models and animations respectively
The usual mechanism for acetal formation is followed and initially the spiroketal forms the axial-equatorial (ax-eq) conformation which equilibrates to the more stable chair-chair axial-axial (ax-ax) conformation.
J. E. Aho, P. M. Pihko and T. K. Rissa, Chem. Rev., 2005, 105, 4406–4440.
F. Perron and K. F. Albizati, Chem. Rev., 1989, 89, 1617–1661.
Click on a star to rate it!
Average rating 2 / 5. Vote count: 1
Let us improve this page!
Thanks for your feedback!