Electrophilic aromatic substitution – Friedel-Crafts alkylation

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Friedel-Crafts alkylation usually involves treating benzene with a secondary or tertiary alkyl halide, and the Lewis acid AlCl3. In this example, the Lewis acid removes the chloride atom from the t-BuCl, which then releases the t-Bu cation for the alkylation reaction. Chloride then removes the proton from the cationic intermediate restoring aromaticity.

G. A. Olah, Acc. Chem. Res., 1971, 4, 240–248.

 

How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Provided by the