Vinyl silanes offer a regio- and stereoselective route to alkenes

Vinyl silanes react with electrophiles in a highly regioselective process in which the silicon is replaced by the electrophile at the ipso carbon atom. The stereochemistry of the vinyl silane is important because this exchange usually occurs with retention of geometry as well.

CLICK the examples below to see how E- and Z-vinyl silanes react:

E-vinyl silane

Z-vinyl silane

I. Fleming, A. Barbero and D. Walter, Chem. Rev., 1997, 97, 2063–2192.



How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this page.

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Provided by the