Click the structures and reaction arrows in sequence to view the 3D models and animations respectively
Stereospecific E2 eliminations – two diastereoisomeric chlorides derived from menthol give two different regioisomers of alkene.
Manipulate the conformations to explore the arrangements of the protons and the chlorine. Are they anti-periplanar as required for E2?
Examine the animated energy plots of Diastereoisomer A and Diastereoisomer B to determine the relative energies of the anti-periplanar conformations required for E2 elimination. Observe the very high energy all-axial conformation and how this is avoided by using a twist-boat conformation in the elimination mechanism.
How useful was this page?
Click on a star to rate it!
Average rating / 5. Vote count:
We are sorry that this page was not useful for you!
Let us improve this page!
Thanks for your feedback!