Conjugate Addition of Diethylamine to an Unsaturated Nitrile (Acrylonitrile)

Conjugate addition mechanism

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Amines are excellent at conjugate addition and unsaturated nitriles are excellent conjugate acceptors as the nitrile is relatively unreactive.
Back to more conjugate addition reactions Alternatively, use these links: (Substrate : Nucleophile)

Unsat. nitrile : Amine | Unsat. ester : Amine | Imine : Enamine | Unsat. aldehyde : Thiol

A. G. Csákÿ, G. de la Herrán and M. C. Murcia, Chem. Soc. Rev., 2010, 39, 4080.

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