The Hantzsch synthesis is a four-component reaction between an aldehyde, two equivalents of a β-ketoester and ammonia, followed by oxidation to give a pyridine-3,5-dicarboxylate. Subsequent decarboxylation gives the corresponding pyridines.
‘Click’ the different stages to view the 3D models of the reaction:
Click on a star to rate it!
Average rating / 5. Vote count:
Let us improve this post!
Thanks for your feedback!