Click the structures and reaction arrows in sequence to view the 3D models and animations respectively
The Knoevenagel condensation is the reaction of stabilised carbanions with carbonyl compounds. A secondary amine is used as the base, as it allows partial deprotonation of a 1,3-dicarbonyl compound but not of a normal aldehyde, so self-condensation of the aldehyde is not a problem.
Click on a star to rate it!
Average rating 5 / 5. Vote count: 2
Let us improve this page!
Thanks for your feedback!