Hydrazone formation

Hydrazone Formation Mechanism

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Reaction of carbonyl with hydrazine gives a hydrazone. Hydrazine is more nucleophilic than a regular amine due to a presence of the adjacent nitrogen. Note the similarity to the formation of an oxime reaction. Hydrazones generally form a mixture of geometric isomers.

J. M. Sayer, B. Pinsky, A. Schonbrunn and W. Washtien, J. Am. Chem. Soc., 1974, 96, 7998–8009.

232

How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this page.

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Provided by the