Diels-Alder reaction – Working out which product is endo

Sn2

Click on the structures above for a method for doing this.

In the reaction between hexa-2,4-diene and acrolein two stereoisomers may be formed – endo and exo. The endo product is favoured, but how can we tell which one this is? The easiest way to work this out is by drawing the reactants coming together in 3D.

J. Sauer, Angew. Chemie Int. Ed. English, 1967, 6, 16–33.

()

How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this page.

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Tell us how we can improve this page (in your own language if you prefer)? If you would like a response, please include your email address e.g. [email protected]

Provided by the