Conjugate Addition of Diethylamine to an Unsaturated Ester

Conjugate addition mechanism

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Amines are excellent at conjugate addition and the low reactivity of esters with nucleophiles favours conjugate addition.

Back to more conjugate addition reactions

Alternatively, use these links: (Substrate: Nucleophile)

Unsat. nitrile : Amine | Unsat. ester : Amine | Imine : Enamine | Unsat. aldehyde : Thiol

A. G. Csákÿ, G. de la Herrán and M. C. Murcia, Chem. Soc. Rev., 2010, 39, 4080.


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