Click the structures and reaction arrows in sequence to view the 3D models and animations respectively
Amines are excellent at conjugate addition and the low reactivity of esters with nucleophiles favours conjugate addition.
Back to more conjugate addition reactions
Alternatively, use these links: (Substrate: Nucleophile)
Unsat. nitrile : Amine | Unsat. ester : Amine | Imine : Enamine | Unsat. aldehyde : Thiol
A. G. Csákÿ, G. de la Herrán and M. C. Murcia, Chem. Soc. Rev., 2010, 39, 4080.
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