Hydrazone formation

Hydrazone Formation Mechanism

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Reaction of carbonyl with hydrazine gives a hydrazone. Hydrazine is more nucleophilic than a regular amine due to a presence of the adjacent nitrogen. Note the similarity to the formation of an oxime reaction. Hydrazones generally form a mixture of geometric isomers.

J. M. Sayer, B. Pinsky, A. Schonbrunn and W. Washtien, J. Am. Chem. Soc., 1974, 96, 7998–8009.

232

How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Provided by the