Mitsunobu Reaction Stage 2

NOTE: Important charges and non-bonding electrons are shown throughout the animation except during the transition state phase.

The anion produced in the first stage of the Mitsunobu reaction is basic enough to remove a proton from the formic acid producing the carboxylate anion.

Onto Mitsunobu Stage 3

Back to Mitsunobu Summary

Click the structures and reaction black arrows in sequence to view the 3D models and animations respectively

T. Y. S. But and P. Toy, Chem. - An Asian J., 2007, 2, 1340–1355.


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