Mitsunobu Reaction Stage 1


NOTE: Important charges and non-bonding electrons are shown throughout the animation except during the transition state phase.

In this initial step a nucleophilic attack is made on the azoformaldehyde to produce a anion intermediate that can be stabilised by one of the formaldehyde groups.

Onto Mitsunobu Stage 2

Back to Mitsunobu Summary

Click the structures and reaction black arrows in sequence to view the 3D models and animations respectively

T. Y. S. But and P. Toy, Chem. - An Asian J., 2007, 2, 1340–1355.


How useful was this page?

Click on a star to rate it!

Average rating 5 / 5. Vote count: 1

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Provided by the