Organopalladium Chemistry

The Suzuki Reaction

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NOTE: Important charges and non-bonding electrons are shown throughout the animation except during the transition phase

Suzuki Cycle

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The Suzuki reaction is the palladium-catalysed addition of aryl, vinyl, or substituted vinyl groups to organic halides or triflates.
The mechanism involves the oxidative addition of the halide and a transmetallation with the boronate hydroxide and base which speeds up the reaction. The palladium(0) catalyst is then regenerated in the reductive elimination step to form the product.

 

 

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