NOTE: Important charges and non-bonding electrons are shown throughout the animation except during the transition phase
Click the structures and reaction arrows to view the 3D models and animations respectively
The initial step has to be protonation of the formaldehyde so it can react with the amine. The formation of the iminium ion can be reversed if water is added to the final product. The processes would occur in the same way but in the reverse order.
M. Arend, B. Westermann and N. Risch, Angew. Chemie Int. Ed., 1998, 37, 1044–1070.
We are sorry that this page was not useful for you!
Let us improve this page!
Tell us how we can improve this page (in your own language if you prefer)? If you would like a response, please include your email address e.g. [email protected]