Intramolecular aldol reactions (Enols of nona-2,8-dione)

Enol structures of nona-2,8-dione

Below are shown the structures of the original diketone and its two enol structures, together with their electrostatic surfaces. One will cyclize to form an eight-membered ring, the other a six-membered ring.

(Red represents areas which are electron rich, blue represents areas that are electron poor)

Back to intramolecular aldol summary

P. Hammar, C. Ghobril, C. Antheaume, A. Wagner, R. Baati and F. Himo, J. Org. Chem., 2010, 75, 4728–4736.

W. Gati and H. Yamamoto, Acc. Chem. Res., 2016, 49, 1757–1768.


How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this page.

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Tell us how we can improve this page (in your own language if you prefer)? If you would like a response, please include your email address e.g. [email protected]

Provided by the