Step 1 – Enantioselective Deprotonation
Click the structures and reaction arrows in sequence to view the 3D models and animations respectively
Firstly the isopropyllithium and the Boc-pyrrolidine come together to form a complex with (–)-sparteine. Due to the asymmetric nature of sparteine, the Hs
hydrogen is in a position where it is removed by the isopropyllithium,
giving the enantiospecific alkyllithium.
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