This shows how hydrogenation can occur vis asymmetric activation of racemic TolBINAP-ruthenium complex. Either the S or R ruthenium-TolBINAP complex is unreactive with respect to hydrogenation of ketones. These have (S,S)-DPEN added to it to form monomeric ruthenium-TolBINAP-DPEN complexes. The R,SS cycles is preferred over the S,SS cycle.
Ryoji Noyori and Takeshi Ohkuma, Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones, Angew. Chem. Int. Ed., 2001, 40, 40-73.
We are sorry that this page was not useful for you!
Let us improve this page!
Tell us how we can improve this page (in your own language if you prefer)?