Asymmetric Sulfoxidation Detail

Sn2
()

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

Note: For clarity, the following simplifications were made: (i) dimethyl tartate was used instead of diethyl tartate; (ii) Hünig’s base 3a was replaced by trimethylamine; (iii) cumene hydroperoxide was replaced by methyl hydroperoxide; and (iv) the isopropoxide ligand was replaced by a methoxide ligand.

The dimethyl tartate and trimethyl amine ligands coordinate to the titanium atom along with methyl peroxide to form a complex. The NH group of the methyl imidazole forms a hydrogen bond with an O atom of the dimethyl tartate, holding the molecules in a conformation where they can react stereoselectively.

Back

M. Seenivasaperumal, H.-J. Federsel and K. J. Szabó, Adv. Synth. Catal., 2009, 351, 903–919.

How useful was this page?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this page.

As you found this page useful...

Follow us on social media!

We are sorry that this page was not useful for you!

Let us improve this page!

Tell us how we can improve this page (in your own language if you prefer)? If you would like a response, please include your email address e.g. [email protected]

Provided by the