Wolff-Kishner Reduction: Carbonyl to Alkane

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Jones Oxidation Mechanism

Click the structures and reaction arrows in sequence to view the 3D models and animations respectively

The ketone is first converted to a hydrazone with hydrazine (H2NNH2). This then undergoes reduction by hot concentrated sodium hydroxide. The reaction works due to the thermodynamic stability of N2.

Link to mechanism for hydrazone formation

 

 

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