Radicals

Iodoheptene Radical Cyclisation Endo

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NOTE: Important charges and non-bonding electrons are shown throughout the animation except during the transition state phase.

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The reaction proceeds via an abstraction of iodine by a trimethyltin radical. The chain can then twist into a position to cyclise. The endo cyclisation to form the seven-membered ring is the minor reaction pathway. The abstraction of hydrogen from trimethyltinhydride by the cycloheptyl radical to form the endo product is not shown.

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